Junichi Goto Selected Research

3beta,7beta-dihydroxy-5-cholen-24-oic acid

1/2006

Chemical synthesis of the 3-sulfooxy-7-N-acetylglucosaminyl-24-amidated conjugates of 3beta,7beta-dihydroxy-5-cholen-24-oic acid, and related compounds: unusual, major metabolites of bile acid in a patient with Niemann-Pick disease type C1.

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Junichi Goto Research Topics

Disease

4	Type C Niemann-Pick Disease (Niemann Pick Disease, Type C) 09/2015 - 01/2006
2	Ascites 12/2021 - 07/2006
2	Niemann-Pick Diseases (Niemann Pick Disease) 09/2015 - 09/2009
2	Inflammation (Inflammations) 12/2009 - 03/2008
2	Neoplasms (Cancer) 02/2008 - 11/2005
1	Peritoneal Fibrosis 12/2021
1	Liver Cirrhosis (Hepatic Cirrhosis) 12/2021
1	Small Cell Carcinoma 01/2016
1	Adenocarcinoma 01/2016
1	Digestive System Diseases 09/2015
1	Cardiomegaly (Heart Hypertrophy) 12/2009
1	Hypertension (High Blood Pressure) 12/2009
1	Renal Insufficiency (Renal Failure) 12/2009
1	Fibrosis (Cirrhosis) 01/2009
1	Hernia (Hernias) 01/2009
1	Biliary Liver Cirrhosis (Primary Biliary Cirrhosis) 06/2008
1	Serous Cystadenoma 05/2008
1	Infections 04/2008
1	Stomach Ulcer (Gastric Ulcer) 01/2007
1	Neoplasms, Cystic, Mucinous, and Serous 01/2007
1	Pancreatic Ductal Carcinoma 01/2007
1	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 11/2005
1	Carcinogenesis 12/2004
1	Aberrant Crypt Foci 12/2004
1	Heart Failure 03/2004
1	Cysts 10/2003
1	Diabetes Mellitus 01/2003
1	Hypersensitivity (Allergy) 03/2002
1	Drug-Related Side Effects and Adverse Reactions 01/2002

Drug/Important Bio-Agent (IBA)

6	Bile Acids and Salts (Bile Acids)IBA 09/2009 - 03/2002
3	AcidsIBA 10/2013 - 01/2003
2	Deoxycholic Acid (Sodium Deoxycholate)IBA 07/2006 - 12/2004
1	CholesterolIBA 09/2015
1	Oxidoreductases (Dehydrogenase)IBA 09/2015
1	AmidesIBA 10/2013
1	Biomarkers (Surrogate Marker)IBA 10/2013
1	N,N-dimethylarginine (asymmetric dimethylarginine)IBA 12/2009
1	Uremic ToxinsIBA 12/2009
1	Aconitic Acid (Aconitate)IBA 12/2009
1	Pravastatin (Pravachol)FDA LinkGeneric 12/2009
1	Organic Anion TransportersIBA 12/2009
1	Ursodeoxycholic Acid (Urso)FDA LinkGeneric 06/2008
1	lafutidineIBA 04/2008
1	Pharmaceutical PreparationsIBA 04/2008
1	ProstaglandinsIBA 03/2008
1	N- propyl- 4- phenyl- 1,2,3,6- tetrahydropyridine (PPTP)IBA 01/2007
1	Serum AlbuminIBA 07/2006
1	Carrier Proteins (Binding Protein)IBA 07/2006
1	3beta,7beta-dihydroxy-5-cholen-24-oic acidIBA 01/2006
1	Interleukin-17 (Interleukin 17)IBA 11/2005
1	Biological ProductsIBA 11/2005
1	Kanamycin KinaseIBA 11/2005
1	Lithocholic AcidIBA 12/2004
1	CarcinogensIBA 12/2004
1	Histones (Histone)IBA 12/2004
1	Digoxin (Digitek)FDA LinkGeneric 03/2004
1	Fluorescein (Funduscein)FDA LinkGeneric 10/2003
1	Lysine (L-Lysine)FDA Link 10/2003
1	GlucuronidesIBA 03/2002
1	Proteins (Proteins, Gene)FDA Link 03/2002
1	Isoniazid (Ftivazide)FDA LinkGeneric 01/2002

Therapy/Procedure

2	Pancreatectomy 05/2008 - 01/2007
1	Peritoneal Dialysis 12/2021
1	Catheters 12/2021
1	Gastrectomy 01/2016
1	Therapeutics 12/2009
1	Herniorrhaphy 01/2009
1	Drug Therapy (Chemotherapy) 02/2008
1	Splenectomy 01/2007